Nicotine, feem ntau hu ua nicotine, yog ib qho muaj zog parasympathomimetic alkaloid pom nyob rau hauv cov nroj tsuag Solanaceae. Nws yog cov tshuaj lom neeg tseem ceeb thiab cov khoom siv tseem ceeb ntawm cov luam yeeb thiab ib hom tshuaj stimulant.
Xyoo 1828, German chemists Posselt thiab Reimann thawj zaug cais nicotine los ntawm luam yeeb. Xyoo 1843, Melsens tau npaj cov tshuaj nicotine. Nyob rau hauv 1893, Adolf Pinner nrhiav tau tus qauv ntawm nicotine, thiab nyob rau hauv 1904 A. Pictet thiab Crepieux tau ntse tau nicotine los ntawm synthesis.
Artificially synthesized nicotine yog tau los ntawm kev taw qhia synthesis los ntawm ntau cov kauj ruam ntawm cov tshuaj tiv thaiv nyob rau hauv tej yam kev mob tshwm sim siv cov kev tshawb xav ntawm organic thiab tshuaj synthesis, siv cov tshuaj reagents tsim nyog raws li cov ntaub ntawv pib. Synthetic nicotine kiag li tshem tawm xya qhov teeb meem impurities nyob rau hauv luam yeeb-extracted nicotine thiab yog ib tug high-purity, high-cov ntsiab lus dawb crystal.
Txij thaum ntawd los, tib neeg tsis tsuas yog tau txais nicotine los ntawm kev rho tawm los ntawm luam yeeb. Tab sis tib lub sijhawm, cov lus nug tshiab tau tshwm sim rau cov khoom lag luam luam yeeb thiab cov kev tswj hwm muaj feem cuam tshuam - hluavtaws nicotine tsis tuaj ntawm cov luam yeeb, yog li nws puas suav tias yog cov khoom luam yeeb?